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WALKER, CHERYL

One or more keywords matched the following items that are connected to WALKER, CHERYL

Item Type	Name
Concept	Tuberous Sclerosis
Academic Article	Activity of TSC2 is inhibited by AKT-mediated phosphorylation and membrane partitioning.
Academic Article	AMP-activated protein kinase signaling results in cytoplasmic sequestration of p27.
Academic Article	ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS.
Academic Article	Loss of inhibitory insulin receptor substrate-1 phosphorylation: An early event in endometrial hyperplasia and progression to carcinoma.
Academic Article	PTEN deficiency is fully penetrant for prostate adenocarcinoma in C57BL/6 mice via mTOR-dependent growth.
Academic Article	Loss of inhibitory insulin receptor substrate-1 phosphorylation is an early event in mammalian target of rapamycin-dependent endometrial hyperplasia and carcinoma.
Academic Article	Loss of tuberous sclerosis complex-2 function and activation of mammalian target of rapamycin signaling in endometrial carcinoma.
Academic Article	Polycystic kidney disease as a result of loss of the tuberous sclerosis 2 tumor suppressor gene during development.
Academic Article	Ral and Rheb GTPase activating proteins integrate mTOR and GTPase signaling in aging, autophagy, and tumor cell invasion.
Academic Article	Estrogen promotes the survival and pulmonary metastasis of tuberin-null cells.
Academic Article	Retention of membrane-localized beta-catenin in cells lacking functional polycystin-1 and tuberin.
Academic Article	Phosphatidylinositol 3-kinase but not tuberin is required for PDGF-induced cell migration.
Academic Article	Lycopene in the prevention of renal cell cancer in the TSC2 mutant Eker rat model.
Academic Article	Reactive nitrogen species regulate autophagy through ATM-AMPK-TSC2-mediated suppression of mTORC1.
Academic Article	TSC2, a key player in tumor suppression and cystic kidney disease.
Academic Article	A tuberous sclerosis complex signalling node at the peroxisome regulates mTORC1 and autophagy in response to ROS.
Academic Article	ATM engages the TSC2/mTORC1 signaling node to regulate autophagy.
Academic Article	Up-regulation of hypoxia-inducible factor 2alpha in renal cell carcinoma associated with loss of Tsc-2 tumor suppressor gene.
Academic Article	Aberrant expression of HMGA2 in uterine leiomyoma associated with loss of TSC2 tumor suppressor gene function.
Academic Article	Cell proliferation is insufficient, but loss of tuberin is necessary, for chemically induced nephrocarcinogenicity.
Academic Article	Carboxy terminal tail of polycystin-1 regulates localization of TSC2 to repress mTOR.
Academic Article	Identification of a sensitive period for developmental programming that increases risk for uterine leiomyoma in Eker rats.
Academic Article	Differential localization of ATM is correlated with activation of distinct downstream signaling pathways.
Academic Article	Tuberin, the tuberous sclerosis complex 2 tumor suppressor gene product, regulates Rho activation, cell adhesion and migration.
Academic Article	Interaction between genetic susceptibility and early-life environmental exposure determines tumor-suppressor-gene penetrance.
Grant	Genetic Determinants of Rat Renal Carcinogenesis
Grant	Gene X Environment Interactions in the Pathogenesis of Uterine Fibroids
Grant	Molecular Etiology of Leiomyoma Uteri
Academic Article	Lymphangioleiomyomatosis and TSC2-/- cells.

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Tuberous Sclerosis